吴定涛 研究员

吴定涛，博士，研究员，硕士生导师

单位：成都大学 食品与生物工程学院

通讯地址：成都大学农业农村部杂粮加工重点实验室202办公室

电子邮箱：wudingtao@cdu.edu.cn；DTWu_carbohydrate@163.com;

工作及教育经历

2021.04 - 至今  成都大学，食品与生物工程学院，研究员

2017.02 - 2021.03  四川农业大学，食品加工与安全研究所，副研究员

2012.09-2017.01  澳门大学，中药机制与质量全国重点实验室，生物医药博士

2009.09-2012.07  合肥工业大学，化学与化工学院，生物化工硕士

2005.09-2009.07  四川轻化工大学，生物工程学院，制药工程学士

主要研究方向

1. 食品功能因子的健康作用与作用机理研究

2. 食药同源资源的质量评价关键技术研究

3. 功能性食品的开发与应用关键技术研究

主要科研情况

现主要从事特色农产品、食药用资源的功能活性因子挖掘及其健康产品开发研究。研究工作获国家自然科学基金、四川省自然科学基金青年项目、四川省自然科学基金青年项目、四川省自然科学基金面上项目、四川省科技计划重点研发项目等课题资助。近年来，相关研究成果已发表SCI论文200余篇，其中以第一作者和通讯作者在食品领域主流期刊上发表SCI论文90余篇，论文总引用次数达12890余次，曾入选ESI高被引论文15篇，连续四年入选“全球前2%顶尖科学家”榜单（食品科学领域）。荣获四川省科技进步二等奖和三等奖各1项、中国食品科学技术学会科技进步二等奖1项。担任Frontiers in Nutrition副编辑，担任International Journal of Biological Macromolecules、Chinese Medicine、Food Innovation and Advances、Food & Medicine Homology、Food Safety and Health、Foods、Antioxidants、Frontiers in Sustainable Food Systems等期刊编委/青年编委/客座编辑。

奖励及荣誉

1. 2025年成都大学优秀硕士学位论文指导教师

2. 2025年四川省科技进步三等奖

3. 2024年中国食品科学技术学会科技进步二等奖

4. 2021年入选第十三批四川省学术和技术带头人后备人选

5. 2019年四川省科技进步二等奖

6. 2019年四川省食品科学技术学会技术发明一等奖

7. 2018年入选四川省海外高层次留学人才

8. 2016年澳门特别行政区科学技术奖励“研究生科技研发奖”

部分代表性论文

全部论文详见https://www.researchgate.net/profile/Dingtao-Wu

1. B. Li, L. Zhang, D.T. Wu *, Q. Yuan, S. Wang, M.L. Tan, M.L. Feng, Y.C. Hu, L. Zou, Z.P. Wang, Y.N. Cao, J.W. Huang*. Potential structure-immunostimulatory activity relationship of Tartary buckwheat sprout pectic polysaccharides: Influences of molecular mass and esterification degree. Food Research International, 2026, 233: 118949.

2. Y. Deng, J. Lei, X. Luo, S.P. Wang, H.M. Tan, J.Y. Zhang, D.T. Wu *. Prospects of Ganoderma polysaccharides: Structural features, structure-function relationships, and quality evaluation. International Journal of Biological Macromolecules, 2025, 309: 142836.

3. K.X. Jiang, J.L. Geng, Q. Yuan, J. Li, W. Li, H.Y. Liu, Y.C. Hu, L. Zou, S. Wang, D.T. Wu *. Pectic polysaccharides from unripe and mature kiwifruit alleviate ulcerative colitis by modulating gut microbiota and restoring the intestinal barrier. Food Bioscience, 2025, 71: 107315.

4. W. Guo, B. Li, M.Q. Wang, Y. Cao, Q. Yuan, W. Liu, Y.C. Hu, L. Zou, S. Wang, D.T. Wu *. Impact of esterification degree of pectic polysaccharides from quinoa microgreen on protective effects against dextran sulfate sodium-induced colitis in mice. Food Bioscience, 2025, 74: 107877.

5. J. Feng, X. Luo, B. Li, X.Y. Yang, L. Zhang, J.W. Huang, Y.C. Hu, L. Zou, D.T. Wu *. Chemical structures, antioxidant capacities, and immunostimulatory activities of pectic polysaccharides from jujube fruits collective from different producing areas. Food Bioscience, 2025, 68: 106485.

6. Y.J. Huang, J. Feng, Y. Deng, J. Li, H.Y. Liu, Q. Liang, Y.C. Hu, J.Y. Zhang, L. Zou, D.T. Wu *. The degree of esterification influences the bioactivity of pectic polysaccharides isolated from Lithocarpus litseifolius. Food Chemistry: X, 2025, 27: 102462.

7. J.L. He, K.X. Jiang, T. Wei, J.L. Geng, Z.F. Zhao, J. Feng, J. Li, H.Y. Liu, S. Lin, D.T. Wu *. Comparative analysis of pectic polysaccharides isolated from various thinned young red-fleshed kiwifruits: Structural properties and biological functions. Food Chemistry: X, 2025, 29: 102709.

8. Q. Yuan, W. Liu, W. Hao, Y. Chen, Y.Q. Xiao, H.Y. Li, M.J. Shui, D.T. Wu *, S.P. Wang*. Glycosidic linkages of fungus polysaccharides influence the anti-inflammatory activity in mice. Journal of Advanced Research, 2025, 67: 161-172

9. D.T. Wu *, J. Li, J. Wang, J. Lei, R.Y. Gan, P.Y. Qin, Y.C. Hu, X.Y. Wu, L. Zou*. Comparison of soluble dietary fibers from various quinoa microgreens: Structural characteristics and bioactive properties. Food Research International, 2024, 181: 114108.

10. J. Li, J. Feng, X. Luo, M.M. Qu Mo, W.B. Li, J.W. Huang, S.P. Wang, Y.C. Hu, L. Zou, D.T. Wu *. Potential structure–function relationships of pectic polysaccharides from quinoa microgreens: Impact of various esterification degrees. Food Research International, 2024, 187: 114395.

11. W.B. Li, J. Wang, M.M. Qu Mo, J. Li, M. Li, Y. Liu, S.P. Wang, Y.C. Hu, L. Zou, D.T. Wu *. Pectic polysaccharides from Tartary buckwheat sprouts: Effects of ultrasound-assisted Fenton treatment and mild alkali treatment on their physicochemical characteristics and biological functions. Ultrasonics Sonochemistry, 2024, 109: 107014.

12. W.B. Li, J. Lei, M.M. Qu Mo, J. Li, J. Wei, Y. Liu, S.P. Wang, Y.C. Hu, L. Zou, D.T. Wu *. Impacts of ultrasound-assisted Fenton degradation and alkaline de-esterification on structural properties and biological effects of pectic polysaccharides from Tartary buckwheat leaves. Ultrasonics Sonochemistry, 2024, 106: 106895.

13. J. Wang, J. Li, X. Luo, M.M. Qu Mo, J. Feng, W.B. Li, H. Yan, Y.C. Hu, L. Zou, D.T. Wu *. Structural properties and biological effects of pectic polysaccharides extracted from Tartary buckwheat sprouts by high pressure-assisted deep eutectic solvent extraction. LWT - Food Science and Technology, 2024, 203: 116397.

14. W. Deng, Q.N. Yang, H.Y. Liu, Y. Xia, H. Yan, J.W. Huang, Y.C. Hu, L. Zou, R.Y. Gan, D.T. Wu *. Comparative analysis of phenolic compounds in different thinned unripe kiwifruits and their biological functions. Food Chemistry: X, 2024, 24: 101815.

15. R.Y. Gan*, Y. Liu, H. Li, Y. Xia, H. Guo, F. Geng, Q.G. Zhuang, H.B. Li, D.T. Wu *. Natural sources, refined extraction, biosynthesis, metabolism, and bioactivities of dietary polymethoxyflavones (PMFs). Food Science and Human Wellness, 2024, 13: 27-49.

16. D.T. Wu *, J.L. Geng, J. Li, W. Deng, Y. Zhang, Y.C. Hu, L. Zou, Y. Xia, Q.G Zhuang, H.Y. Li*, R.Y. Gan. Efficient extraction of pectic polysaccharides from thinned unripe kiwifruits by deep eutectic solvent-based methods: Chemical structures and bioactivities. Food Chemistry: X, 2024, 21: 101083.

17. D.T. Wu *, J. Wang, J. Li, J.L. Hu, H.L. Yan, J.L. Zhao, L. Zou, Y.C. Hu*. Physicochemical properties and biological functions of soluble dietary fibers isolated from common and Tartary buckwheat sprouts. LWT - Food Science and Technology, 2023, 183: 114944.

18. Y.C. Hu, J.L. Hu, J. Li, J. Wang, X.Y. Zhang, X.Y. Wu, X. Li, Z.B. Guo, L. Zou, D.T. Wu *. Physicochemical characteristics and biological activities of soluble dietary fibers isolated from the leaves of different quinoa cultivars. Food Research International, 2023, 163: 112166.

19. D. Liu, X.-Q. He, D.T. Wu *, H.-B. Li, Y.-B. Feng, L. Zou, R.-Y. Gan*. Elderberry (Sambucus nigra L.): Bioactive compounds, health functions, and applications. Journal of Agricultural and Food Chemistry, 2022, 70(14): 4202-4220.

20. D.T. Wu *, Y. He, Q. Yuan, S.P. Wang, R.-Y. Gan, Y.-C. Hu, L. Zou*. Effects of molecular weight and degree of branching on microbial fermentation characteristics of okra pectic-polysaccharide and its selective impact on gut microbial composition. Food Hydrocolloids, 2022, 132: 107897.

21. D.T. Wu *, L.-Y. An, W. Liu, Y.-C. Hu, S.P. Wang, L. Zou*. In vitro fecal fermentation properties of polysaccharides from Tremella fuciformis and related modulation effects on gut microbiota. Food Research International, 2022, 156: 111185.

22. D.T. Wu *, Y. He, M.-X. Fu, R.-Y. Gan, Y.-C. Hu, L.-X. Peng, G. Zhao, L. Zou*. Structural characteristics and biological activities of a pectic-polysaccharide from okra affected by ultrasound assisted metal-free Fenton reaction. Food Hydrocolloids, 2022, 122: 107085.

23. D.T. Wu *, X.-R. Nie, R.-Y. Gan, H. Guo, Y. Fu, Q. Yuan, Q. Zhang, W. Qin*. In vitro digestion and fecal fermentation behaviors of a pectic polysaccharide from okra (Abelmoschus esculentus) and its impacts on human gut microbiota. Food Hydrocolloids, 2021, 144: 106577.

24. D.T. Wu *, Q. Yuan, H. Guo, Y. Fu, F. Li, S.-P. Wang, R.-Y. Gan*. Dynamic changes of structural characteristics of snow chrysanthemum polysaccharides during in vitro digestion and fecal fermentation and related impacts on gut microbiota. Food Research International, 2021, 141: 109888.

25. Q. Yuan, Y. He, P.-Y. Xiang, S.-P. Wang, Z.-W. Cao, T. Gou, M.-M. Shen, L. Zhao, W. Qin, R.-Y. Gan, D.T. Wu *. Effects of simulated saliva-gastrointestinal digestion on the physicochemical properties and bioactivities of okra polysaccharides. Carbohydrate Polymers, 2020, 238: 116183.