报告题目：有机硼新试剂及合成方法学的开发与应用 (New reagents and methodologies in the synthesis and application of organoboron compounds)
报告人：Prof. 吕海荣 (Hairong Lyu)；香港中文大学 (The Chinese University of Hong Kong)
报告时间：2026年11月06日16:00-17:00 (邀请人：明佳林)
报告地点：中国–东盟艺术学院 A 栋 A1018 学术报告厅（东盟小礼堂）
报告内容简介：有机硼化合物在合成化学、生物医学和材料科学中已得到广泛应用。有机硼化合物的合成及其下游转化持续吸引着大量研究兴趣，而这些进展依赖于新型硼试剂和方法学的发展。然而，尽管已取得相当大的进展，成熟且被广泛使用的硼试剂范围仍然有限，从而限制了这些试剂所能提供的反应模式的多样性。吕海荣教授团队合成了一系列新型中性sp²-sp³二硼试剂，并探索了它们作为硼化试剂和硼合成子前体的性质。我们还研究了它们在合成化学中的应用，证明其有望成为有机硼化合物合成与官能化的有价值工具。此外，我们报道了一种电化学驱动的Matteson型同系化反应，为该反应自发现以来长期存在的挑战提供了一种概念验证性解决方案。
Organoboron compounds have found broad applications in synthetic chemistry, biomedicine, and materials science. The synthesis of organoborons and their downstream transformations, which continue to attract significant research interest, rely on the development of new boron reagents and methodologies. However, despite considerable advancements, the range of well-established and widely utilized boron reagents remains limited, thereby constraining the diversity of reaction modes available from these reagents. Recently, Prof. Hairong Lyu synthesized a series of new neutral sp²-sp³ diboron reagents and explored their properties as borylation agents and precursors for boron synthons. We also investigated their applications in synthetic chemistry, demonstrating their potential as valuable tools for the synthesis and functionalization of organoboron compounds. Furthermore, we reported an electrochemically driven Matteson-type homologation, providing a proof-of-concept solution to the longstanding challenges associated with this reaction since its discovery.
